Dumaguete Info Search


Welcome!

By registering with us, you'll be able to discuss, share and private message with other members of our community.

Best Posts in Thread: Medial grade **********

  1. Notmyrealname

    Notmyrealname DI Forum Luminary Highly Rated Poster Showcase Reviewer

    Joined:
    Oct 25, 2016
    Messages:
    4,994
    Likes Received:
    1,848
    I would have serious concerns about using this drug in treating Covid-19 if only because "********** has been shown to inhibit the replication of SARS-CoV-2 in cell cultures. However, pharmacokinetic and pharmacodynamic studies suggest that achieving the plasma concentrations necessary for the antiviral efficacy detected in vitro would require administration of doses up to 100-fold higher than those approved for use in humans." (https://www.covid19treatmentguidelines.nih.gov/therapies/antiviral-therapy/**********/)

    Although I have not chosen this drug as the best of all possibilities (because I don't know all the possibilities), I would be thinking more about dexamathasone. Various sources state is it ALREADY "used to treat rheumatic problems, a number of skin diseases, severe allergies, asthma, chronic obstructive lung disease, croup, brain swelling, eye pain following eye surgery, and along with antibiotics in tuberculosis."

    "Dexamethasone is a corticosteroid used in a wide range of conditions for its anti-inflammatory and immunosuppressant effects.

    It was tested in hospitalized patients with COVID-19 in the United Kingdom’s national clinical trial RECOVERY and was found to have benefits for critically ill patients.

    According to preliminary findings shared with WHO (and now available as a preprint), for patients on ventilators, the treatment was shown to reduce mortality by about one third, and for patients requiring only oxygen, mortality was cut by about one fifth."
    (https://www.who.int/news-room/q-a-detail/coronavirus-disease-covid-19-dexamethasone)
     
    • Informative Informative x 2