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Breakthrough in UK for covid 19 treatment.

Discussion in 'COVID-19' started by DavyL200, Jul 26, 2020.

  1. DavyL200

    DavyL200 DI Forum Luminary ★ Global Mod ★ Highly Rated Poster Showcase Reviewer

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    From left: Southampton professors Ratko Djukanovic, Donna Davies and Stephen Holgate, founded Synairgen decades ago after finding patients’ defences against viruses could be boosted if a missing protein were replaced.

    Three professors at the University of Southampton school of medicine have this week made a “major breakthrough” in the treatment of coronavirus patients and become paper millionaires at the same time.

    Almost two decades ago professors Ratko Djukanovic, Stephen Holgate and Donna Davies discovered that people with asthma and chronic lung disease lacked a protein called interferon beta, which helps fight off the common cold. They worked out that patients’ defences against viral infection could be boosted if the missing protein were replaced.

    The academics created a company, Synairgen, to turn their discoveries into treatments. It floated on the stock market in 2004, but a deal with AstraZeneca to treat viral infections in asthmatics fell through, and the shares collapsed.

    Fast-forward a few years to the coronavirus pandemic, however, and suddenly any potential therapeutics for breathing difficulties were in high demand.

    Richard Marsden, Synairgen’s chief executive, said the company had been deeply involved in a trial using the interferon beta drug to help people with chronic bronchitis or emphysema. “[But] when the coronavirus pandemic emerged, even back in January we realised that we might have an important role to play in defence against this virus,” he said. “So we set about getting a clinical trial set up in February and March in anticipation of the virus coming to the UK, [and] it did. The trial was in place when people started to fill the hospitals up.

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  2. Notmyrealname

    Notmyrealname DI Forum Luminary Highly Rated Poster Showcase Reviewer

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    Hope this work leads to a good outcome.

    I read something on this a while ago and it mentioned using a nebuliser to blow it directly into the lungs.

    BUT, about 50 years ago I read about interferon and it was to become the wonder drug to cure ALL (or maybe 'most') vital infections, as it is non-specific.

    This would have been as great a benefit as finding penicillin for use against bacteria.

    As of yet, it has never held up its promise (same as chemical baldness cures which were 'just around the corner' decades ago!).

    But anything that contributes to a 'cure' or helps in any meaningful way has to be appreciated.

    Currently, the Oxford vaccine seems one of the most promising - but time will tell.
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