The final sentence of this article is of great interest, bearing in mind the proven ability of the virus to mutate.
COVID-19 vaccines: Where is PH in the procurement, clinical trials? By Eimor Santos, CNN Philippines, Jan 9, 2021
A few points from this article:
Authorities are in talks with around seven vaccine makers to secure 148 million doses, enough to inoculate up to 70 million people.
Officially, no vaccine has been delivered yet to the country to date, but the World Health Organization said in a January 6 media briefing, the country is “on track” in preparing for the rollout.
There are two ways vaccines could reach Filipinos. One is through procurement, which is being handled exclusively by the national government, although tripartite agreements can be entered into by the private sector and local government officials. The other is through phase 3 clinical trials.
Here’s a rundown of where the Philippines now stands on the road to vaccination:
In November 2020, the country sealed the deal for 2.6 million doses from UK's AstraZeneca through a private sector donation. These are expected to be delivered in June of this year, benefiting more than a million Filipinos, with healthcare workers and vulnerable sectors given priority. Half of the purchase will go to the government, while the other half will be used by the private sector, also for their frontliners.
Over 200 companies are expected to pitch in for a second batch, which would complete the targeted 5 million vaccine doses.
In another tripartite agreement, the Quezon City government purchased in advance 750,000 doses of AstraZeneca’s vaccines for its constituents.
Bacolod City said it has signed a "confidential" agreement with AstraZeneca - it has earmarked ₱300 million for the purchase of the vaccines.
The Food and Drug Administration is still reviewing AstraZeneca’s application for emergency use authorization, which would fast track the rollout of its vaccine in the country. US firm Pfizer and Russia’s Gamaleya Institute are also seeking EUA.
Vaccine czar Carlito Galvez, Jr. recently said the government is in the “advanced stages of negotiations” with Pfizer, Gamaleya, American pharmaceutical companies Novavax and Johnson and Johnson, and Chinese drugmaker Sinovac.
The Duterte administration believes Sinovac would be the first to supply the Philippines with up to 25 million doses by March or April 2021. It has a pending application for clinical trials.
The country will also receive "fully subsidized" COVID-19 vaccines for 22 million Filipinos through the COVAX facility, a global initiative led by the WHO along with the vaccine alliance Gavi and the Coalition for Epidemic Preparedness Innovations to ensure equitable access to safe and effective coronavirus vaccines.
An allegedly bungled deal with Pfizer, which boasts of a vaccine efficacy rate of 95%, would have ushered the arrival of 10 million doses this month - officials now estimate the supply to come in by mid-year.
Two other US firms, Moderna and Arcturus expressed willingness to send 4 million to 25 million vaccine doses beginning the third quarter, but this has not been put in paper.
Meanwhile, Filipinos could volunteer for clinical trials soon, after the FDA approved the applications of Janssen Pharmaceuticals Company, a US-based vaccine maker owned by Johnson & Johnson, and Clover Biopharmaceutical of China. These may start in the next few weeks after the vaccine experts panel identifies trial sites and participants are recruited.
Aside from these independent initiatives, the World Health Organization’s Solidarity Trial is slated for this month, but it remains unclear which vaccines it would test for efficacy. Galvez said it would enroll up to 15,000 volunteers, preferably from Metro Manila.
The country remains under varying levels of community quarantine – all face-to-face classes suspended, business operations limited, and work-from-home setup encouraged. It is banking on the vaccination program to further open the economy, but health protocols should still be followed as it may take three to five years to inoculate enough people to achieve herd immunity.
Best Posts in Thread: Vaccine in Philippines
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Here's the information you should know in relation to the anti-COVID-19 vaccinations that could possibly arrive in the country this year.
- Today the Food and Drug Administration (FDA) has approved the application of Pfizer-BioNTech to have emergency use authorization for their vaccine here in the Philippines. ( http://bit.ly/3bxrrh8)
- One of the most expensive Sinovac vaccinations with only 50 % efficiency rate will arrive in the country this February, according to DOH Sec. Doque. ( http://bit.ly/39h1xeS)
- Remember that some members of the Presidential Security Group (PSG) had illegal vaccination using Sinopharm vaccine from China. ( http://bit.ly/3bExm4a) According to Defense chief Delfin Lorenzana, it can be considered ′′ smuggled ′′ because it did not go through the right process. ( http://bit.ly/3qwdqVl) PSG's defense, they only did it to protect the president. ( https://bit.ly/2KdtUC9)
(Information regarding vaccine price is from Sen's office. Awesome) this is a translation
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If this vaccine increases the risk of death people need to know about it. We have already set the standard that age and existing health conditions don't matter when it comes to COVID. Everyone should be fearful of this virus no matter how low the risk factor is for their demographic. The same standards should apply to the vaccines. Every life matters and we cannot take any risk that would prematurely end one of these lives...even if it is only by a few days/weeks/months/years/decades.
However, those links provided really seem like they are trying to appeal to emotion. I don't give a crap about individual or anecdotal evidence. People have reactions to vaccines, it is just part of it. When you have millions/billions getting vaccinated even a tiny percentage will result in thousands/millions having a reaction. These reports mean absolutely nothing on their own and are completely normal and expected when you vaccinate a huge number of people.
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Ah, here it is on Quora, with answers and a link to the note on slide 6 of the presentation. You are not talking to shlocks here.
"There were indeed 3150 people unable to perform daily activities due to the virus. This does not mean that they never regained those abilities again. Most likely, they bounced back in a couple days. When you get your vaccine, leave a couple days to recover. If you need to, take an anti inflammatory for the pain (aspirin, naproxen, etc).
From the prior documentation on the vaccine, there are expected to be a number of short term side effects, such as soreness, migraine, flu like symptoms, etc. These can be severe enough to make it hard to continue daily activities for 18 to 24 hours. It is recommended that patients have a couple days to recover from the vaccine before doing anything that requires high level thought. This is fairly normal. It is the effects of the body learning how to generate the right antibodies for the virus and preparing the immune system to fight the virus. After that, the effects go away. This will happen to some extent with any vaccine.
As with any system insult, anaphylaxis is a problem for those with severe allergies. This is easily treated with epinephrine, antihistamines, and a steroid if caught in time. Recovery takes anything from an hour or two to about 3 days, but recovery is fairly certain with good treatment.
There has been some talk about people being allergic to some component. While this is possible, it is likely that in people with known severe allergies that the body simply goes overboard with any sort of insult.
Because the vaccine presents a very specific feature from the virus (or something similar), the immune system will learn that one feature. By choosing that feature correctly, scientists can minimize the likelihood of other issues. Actually, it contains messenger RNA which tells some cells to produce the spike that is on the virus. The body learns to attack that spike.
If you got the regular virus, the immune system could attack any and all features of the virus, thus requiring it to learn several responses. One of those responses could be against a feature that is similar to something else in the body, thus leading to autoantibodies. This leads to long term effects.
After 12 days, the positive effects of the vaccine kick in, and the likelihood of getting sick with covid-19 drop to very nearly zero.
Note that this vaccine contains neither preservatives nor mercury. The no preservatives part means it needs to be kept cold."
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CDC: Adverse reactions are usually mild to moderate in intensity and resolve within a few days. The most common adverse reactions reported after vaccination in clinical studies included:
- Pain at injection site (84.1%)
- Fatigue (62.9%)
- Headache (55.1%)
- Muscle pain (38.3%)
- Chills (31.9%)
- Joint pain (23.6%)
- Fever (14.2%)
- Injection site swelling (10.5%)
- Injection site redness (9.5%)
- Nausea (1.1%)
- Malaise (0.5%)
- Lymphadenopathy (0.3%)
So it looks like you may be talking about the symptoms that may occur on the second shot that disappear after a few days.
- Informative x 3
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